Latest research confirms safety of mRNA vaccines during pregnancy

Both safe and effective were found the mRNA vaccines against SARS Cov-2, according to a new study, evaluating all relevant previous studies and reviewing their results. The researchers point out that, in total, over 100000 women were vaccinated against Covid-19 during pregnancy, with vaccines protecting from SARS-Cov-2 infection in up to 90% of pregnant women, as early as 7 days after the second dose of the vaccine. Reassuringly, pregnancy complications have not been  any different, between vaccinated and unvaccinated women, with the notable exception of 15% reduction of stillbirths in pregnant women that were vaccinated with mRNA vaccines during pregnancy. All other outcomes, including miscarriage, risk of preterm birth and risk intensive care unit admission, were apparently similar.

Although there were certain limitations in the quality of various studies that were examined by the researchers, it is important to note the association between vaccination against Covid19 and the reduced risk of stillbirth. Covid19 can be a serious infection and among many documented complications during pregnancy, stillbirth can be a devastating event both for the pregnant mother, as well as her health care providers. 

While many pregnant women were reluctant to be vaccinated due to limited available data at the time of the vaccine roll-out, it appears that in a large number of pregnant women not only it has proven effective, but also safe, as no more frequent complications have been documented. If anything, serious complications, such as the risk of stillbirth appear to be reduced in significant numbers.

Reference:

S Prasad. “Systematic review and meta-analysis of the effectiveness and perinatal outcomes of COVID-19 vaccination in pregnancy” (doi.org/10.1038/s41467-022-30052)

©2021, Nicholas Christoforidis, Fertility Matters
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